Concentric hypertrophy is due to pressure overload, while eccentric hypertrophy is due to volume overload.
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These compensatory changes, termed " concentric hypertrophy, " reduce the increase in wall tension observed in aortic stenosis.
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In the heart, concentric hypertrophy is related to increased pressure overload of the heart, often due to hypertension and / or aortic stenosis.
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The type of hypertrophy most commonly seen in AS is known as concentric hypertrophy, in which the walls of the LV are ( approximately ) equally thickened.
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Chronic pressure overload leads to concentric hypertrophy of the cardiac muscle, which can in turn lead to heart failure, myocardial ischaemia or, in extreme cases, outflow obstruction.
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Sarcomeres are added in series, as for example in dilated cardiomyopathy ( in contrast to hypertrophic cardiomyopathy, a type of concentric hypertrophy, where sarcomeres are added in parallel ).
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